|
Symbol Name ID |
Relb
avian reticuloendotheliosis viral (v-rel) oncogene related B MGI:103289 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Neutrophilia |
Impaired lymphocyte transformation with phytohemagglutinin |
Recurrent upper respiratory tract infections |
Recurrent otitis media |
Recurrent urinary tract infections |
Skin rash |
Recurrent pneumonia |
Asthma |
| Disease(s) Associated with RELB | ||||||||
| immunodeficiency 53 |
| Mouse Phenotypes | immune system phenotype |
decreased B cell proliferation |
impaired neutrophil phagocytosis |
intestinal inflammation |
salivary gland inflammation |
stomach inflammation |
thymus atrophy |
thymus hypoplasia |
ovary inflammation |
increased spleen weight |
spleen hyperplasia |
myeloid hyperplasia |
increased eosinophil cell number |
decreased dendritic cell number |
decreased T cell number |
abnormal gamma-delta T cell morphology |
increased spleen red pulp amount |
decreased spleen white pulp amount |
abnormal immunoglobulin level |
increased IgE level |
increased IgM level |
abnormal cytotoxic T cell physiology |
abnormal macrophage physiology |
abnormal cytokine level |
abnormal interferon level |
abnormal interleukin level |
abnormal tumor necrosis factor level |
abnormal immune system organ morphology |
abnormal lymph node morphology |
abnormal mesenteric lymph node morphology |
abnormal immune system physiology |
decreased susceptibility to type IV hypersensitivity reaction |
abnormal cell-mediated immunity |
abnormal humoral immune response |
decreased interleukin-17 secretion |
liver inflammation |
myositis |
epididymis inflammation |
lung inflammation |
dermatitis |
increased susceptibility to bacterial infection |
increased susceptibility to Riboviria infection |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||||
| Relbshep/Relbshep | |||||||||||||||||||||||||||||||||||||||||||
| Relbtm1Brv/Relbtm1Brv | |||||||||||||||||||||||||||||||||||||||||||
| Relbtm1.1Fwei/Relbtm1.1Fwei Tg(Lck-cre)I57Jxm/0 (conditional) |
* | ||||||||||||||||||||||||||||||||||||||||||
| Relbtm1.1Fwei/Relbtm1.1Fwei Tg(Cd4-cre)1Cwi/0 (conditional) |
* | ||||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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